Research
Energy balance
Patient factors potentially contributing to increased aspiration risks included a higher body mass index, type 2 diabetes mellitus, gastro-oesophageal reflux disease, emergency case, and time from GLP-1 agonist cessation.
Understanding these risk factors can help clinicians better assess patients on GLP-1 agonists before surgery.
StrongSupportsmedium confidence
Patient factors potentially contributing to increased aspiration risks in these incidents included a higher body mass index, type 2 diabetes mellitus, gastro-oesophageal reflux disease, emergency case, and time from GLP-1 agonist cessation.
Why this rating
Based on the reporting of specific patient factors in the incidents.
Source
A case series of incidents reported to webAIRS relating to glucagon-like peptide 1 agonist use
C.Y.W. Lam et al. · Anaesthesia and Intensive Care · 2025
DOI 10.1177/0310057x241311597
case_studyCited 2×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Among 11,700 reports from July 2009 to April 2024, 13 incidents related to GLP-1 agonist use were identified, including seven cases concerning aspiration.Strong
- Interdisciplinary collaboration and communication between anaesthetists, surgeons, general practitioners, and endocrinologists are required to further investigate and establish preoperative guidelines for safe GLP-1 agonist use.Strong
Related findings · Energy balance
- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →