Research
Metabolic adaptation
The HLC diet was more effective for improving the triglyceride to HDL-cholesterol ratio (TG/HDL-C) compared to the HLF diet.
The HLC diet may be preferred for improving lipid profiles in overweight adults.
StrongSupportsmedium confidence
The improvement in TG/HDL-C was greater for HLC (p = 0.013).
Why this rating
Based on a large randomized trial with significant participant numbers.
Source
Abstract P226: Improved Insulin Sensitivity with a Healthy Low Fat or a Healthy Low Carbohydrate Weight Loss Diet: A Twelve Month Randomized Trial
John F. Trepanowski et al. · Circulation · 2017
DOI 10.1161/circ.135.suppl_1.p226
rct · n=609Cited 1×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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