Research

Hormonal

NN501 causes weight loss without causing obvious aversive responses.

NN501 may provide a weight loss option without the side effects commonly associated with other treatments.

StrongSupportsmedium confidence
Weight reduction is similar to that of glucagon-like peptide 1 (GLP-1) receptor agonists, but with only a modest effect on food intake.
Claire H. Feetham et al. · Cell Metabolism · 2025

Why this rating

Based on the study design from the abstract.

Source

Analog of prolactin-releasing peptide reduces body weight primarily through sustained fatty acid oxidation rather than hypophagia

Claire H. Feetham et al. · Cell Metabolism · 2025

DOI 10.1016/j.cmet.2025.10.021

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DOI resolved against Crossref · corpus check 2026-06-10

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