Research
Metabolic adaptation
Achieving ≥ 5% total weight loss (TWL) is associated with a higher risk ratio (RR) of type 2 diabetes remission (RR = 7.88).
Practitioners should encourage patients to aim for at least 5% weight loss to improve diabetes remission rates.
StrongSupportsmedium confidence
Compared to < 5%TWL, ≥ 5%TWL had a higher RR of type 2 diabetes remission (RR = 7.88: 95% CI = 5.00, 12.43; I 2 = 75.2%).
Why this rating
Based on meta-analysis of comparative studies.
Source
Effect of Clinically Significant Weight Loss on Remission of Metabolic Complications: A Rapid Review and Meta‐Analysis of Comparative Controlled Studies
Srividya Adapa et al. · Obesity Reviews · 2026
Meta-analysisCited 1×
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