Research
Hormonal
Reoperation odds among ACDF/GLP-1RA patients were significantly reduced at 12 months (4% vs. 6%; OR=0.689) and 24 months postoperatively (5% vs. 7%; OR=0.692).
GLP-1RAs may help reduce the need for reoperation in ACDF patients.
StrongSupportsmedium confidence
Reoperation odds among ACDF/GLP-1RA patients were significantly reduced at 12 months (4% vs. 6%; OR=0.689; 95%CI=0.493-0.963) and 24 months postoperatively (5% vs. 7%; OR=0.692; 95%CI=0.512-0.934).
Why this rating
Based on a retrospective cohort study design with a large sample size.
Source
The Effect of GLP-1 Receptor Agonists on Reoperation Following Anterior Cervical Discectomy and Fusion
Norman Bank et al. · World Neurosurgery · 2025
DOI 10.1016/j.wneu.2025.124751
cohort · n=3184Cited 1×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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