Research

Metabolic adaptation

Liraglutide did not have measurable effects on lean or bone tissue over the 18-day period.

Liraglutide may not affect muscle or bone mass in the short term.

StrongSupportsmedium confidence
with no changes in lean or bone compartments over 18 days.
Valeria Gutierrez de Piñeres et al. · Diabetes Obesity and Metabolism · 2025

Why this rating

Based on the randomized, double-blind, placebo-controlled trial design.

Source

Effects of liraglutide treatment for 18 days on metabolic parameters, regional body composition and the myostatin–activin–follistatin– <scp>IGF</scp> ‐1 axis: Results from an exploratory, randomized, placebo‐controlled, crossover study

Valeria Gutierrez de Piñeres et al. · Diabetes Obesity and Metabolism · 2025

rct · n=20Cited 1×
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