Research

Energy balance

Weight-reduced patients lost 7.2% total body weight (TBW) versus 10.3% in non-weight-reduced patients (p < 0.001).

Practitioners should consider weight-reduction status when evaluating weight loss outcomes with tirzepatide.

StrongSupportsmedium confidence
Weight-reduced patients (n = 133) lost 7.2% TBW versus 10.3% in non-weight-reduced patients (n = 160; p < 0.001).
Sarah R. Barenbaum et al. · Obesity · 2026

Why this rating

Based on the retrospective cohort study design.

Source

Real‐World Weight‐Loss Outcomes in Weight‐Reduced Patients Treated With Tirzepatide

Sarah R. Barenbaum et al. · Obesity · 2026

DOI 10.1002/oby.70179

cohort · n=293Cited 1×
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DOI resolved against Crossref · corpus check 2026-06-10

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