Mixed
White common bean extract (WCBE) rich in alpha-amylase inhibitor, taken 1.5g before meals, significantly improves glycemic control (HbA1c) and ameliorates diabetic peripheral neuropathy in type 2 diabetes patients over 4 months by remodeling gut microbiota to enrich SCFA-producing bacteria.
If you have Type 2 Diabetes, taking 1.5 grams of white common bean extract half an hour before each meal may help lower your HbA1c and improve nerve health. This supplement works by blocking starch digestion and feeding beneficial gut bacteria that produce short-chain fatty acids, which help regulate blood sugar. It should be used alongside your prescribed medication and dietary guidance, not as a replacement.
Glucose metabolism and diabetic complications showed superior remission in Group W with a 0.721 ± 0.742% decline of glycosylated hemoglobin after 4 months... The proportion of patients with diabetic peripheral neuropathy (Toronto Clinical Scoring System, TCSS ≥ 6) was significantly lower in Group W than in Group C... The enrichment of SCFA-producing bacteria might be responsible for the attenuation of T2D and its complications.
Why this rating
Randomized double-blinded placebo-controlled trial with a relatively large sample size (n=90) and clear statistical significance, though limited to a specific population (T2D patients on sulfonylureas/insulin).
Source
White common bean extract remodels the gut microbiota and ameliorates type 2 diabetes and its complications: A randomized double-blinded placebo-controlled trial
Yuwei Feng et al. · Frontiers in Endocrinology · 2022
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