Micronutrients & recovery
Nicotinamide adenine dinucleotide (NAD+) precursors may improve physical function in older individuals, but this outcome appears independent of changes in skeletal muscle mitochondrial function.
Some NAD+ precursors might help older adults improve physical function, but they likely do not work by fixing mitochondria. If you are using them, understand that their benefit may come from a different biological pathway than mitochondrial-targeting supplements.
While there is evidence that some nicotinamide adenine dinucleotide precursors can improve physical function in older individuals, such an outcome seems unrelated to and independent of changes in skeletal muscle mitochondrial function.
Why this rating
The paper states 'there is evidence' but notes the outcome is 'unrelated' to the main mechanism, suggesting a distinct or secondary pathway.
Source
Mitochondria as Nutritional Targets to Maintain Muscle Health and Physical Function During Ageing
Sophie C. Broome et al. · Sports Medicine · 2024
DOI 10.1007/s40279-024-02072-7
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