Micronutrients & recovery
For menopausal women with osteoporosis, first-line pharmacologic therapies include alendronate, risedronate, zoledronic acid, and denosumab for the prevention of hip, nonvertebral, and vertebral fractures.
If you are a postmenopausal woman at high risk, these four drugs are the gold standard first-line treatments. They significantly reduce the chance of breaking a bone (by 30-70%). Discuss the specific dosing schedule (pill vs. injection) with your doctor, ensuring you also take 1200mg of calcium and 800-1000 IU of Vitamin D daily.
For menopausal women requiring treatment of osteoporosis, alendronate, risedronate, zoledronic acid and denosumab can be used as first-line therapies for prevention of hip, nonvertebral and vertebral fractures [grade A].
Why this rating
Grade A recommendation based on systematic reviews and meta-analyses of randomized trials.
Source
2010 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada: summary
A. Papaioannou et al. · Canadian Medical Association Journal · 2010
DOI 10.1503/cmaj.100771
More from this paper
- Management of osteoporosis should be guided by absolute fracture risk assessment rather than bone mineral density (BMD) alone, utilizing tools like CAROC or FRAX to stratify patients into low, moderate, or high risk categories.Strong
- Exercise involving resistance training and/or weight-bearing aerobic exercise is recommended for those with or at risk for osteoporosis to improve physical function, pain, muscle strength, and balance.Good
- Total daily intake of elemental calcium should be 1200 mg and vitamin D supplementation should be 800-1000 IU daily for adults over age 50 at moderate risk of vitamin D deficiency.Good
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