Research

Micronutrients & recovery

For menopausal women with osteoporosis, first-line pharmacologic therapies include alendronate, risedronate, zoledronic acid, and denosumab for the prevention of hip, nonvertebral, and vertebral fractures.

If you are a postmenopausal woman at high risk, these four drugs are the gold standard first-line treatments. They significantly reduce the chance of breaking a bone (by 30-70%). Discuss the specific dosing schedule (pill vs. injection) with your doctor, ensuring you also take 1200mg of calcium and 800-1000 IU of Vitamin D daily.

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For menopausal women requiring treatment of osteoporosis, alendronate, risedronate, zoledronic acid and denosumab can be used as first-line therapies for prevention of hip, nonvertebral and vertebral fractures [grade A].
A. Papaioannou et al. · Canadian Medical Association Journal · 2010

Why this rating

Grade A recommendation based on systematic reviews and meta-analyses of randomized trials.

Source

2010 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada: summary

A. Papaioannou et al. · Canadian Medical Association Journal · 2010

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