Research
Molecular
Prostaglandin E2 (PGE2) production was reduced in both CR groups, significantly in the 30% CR group.
Reducing PGE2 through calorie restriction may enhance T cell function.
StrongSupportsmedium confidence
LPS stimulated PGE2 production was reduced in both groups, but reached statistical significance only in the 30% CR group (33% decrease, p<0.05).
Why this rating
The study includes quantitative measures of biochemical production.
Source
Calorie restriction (CR) enhances T cell mediated immune response in overweight men and women
Tanvir Ahmed et al. · The FASEB Journal · 2006
DOI 10.1096/fasebj.20.5.a988-b
rct · n=46
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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