Research
Molecular
Hypercalciuria in patients is significantly associated with hypertension (OR = 2.9, 1.4-6.2) and kidney stone disease (KSD) (OR = 1.9, 1.03-3.5) in first-degree relatives, particularly siblings.
Clinicians should consider hypercalciuria as a risk factor for hypertension and KSD in patients' families.
StrongSupportsmedium confidence
Multivariate-adjusted odds ratios (OR) revealed significant associations between hypercalciuria in patients and hypertension and KSD in first-degree relatives and specifically in siblings (OR and 95% confidence interval for hypertension = 2.9, 1.4-6.2 and for KSD = 1.9, 1.03-3.5).
Why this rating
Based on the use of multivariate-adjusted odds ratios from a well-defined population.
Source
High urinary calcium excretion and familial aggregation of hypertension, kidney stone disease, obesity, excessive weight gain and type 2 diabetes in patients with calcareous stones
Andrew Mente · TSpace · 2007
cohort · n=333
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