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MR-O and Conv-O similarly increased fecal fat percentage from 3.8% to 13.5%, confirming pharmacodynamic equivalence.
Both formulations can be considered equally effective in increasing fecal fat excretion.
StrongSupportsmedium confidence
MR-O and Conv-O similarly increased fecal fat percentage from 3.8% to 13.5%, confirming pharmacodynamic equivalence.
Why this rating
The study involved a randomized, single-blind, crossover trial with healthy volunteers.
Source
A Comparative Analysis of the Pharmacodynamic and Pharmacokinetic Properties of 2 Controlled‐Release Formulations Versus a Marketed Orlistat Product
Stefan Grudén et al. · Clinical Pharmacology in Drug Development · 2025
DOI 10.1002/cpdd.1503
other · n=20
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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