Research
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Sub-chronic administration of 0839 and 0833 reduced food intake and body weight in DIO mice and rats.
These compounds may help in managing weight in populations with diet-induced obesity.
StrongSupportsmedium confidence
Sub-chronically, 0839 and 0833 had comparable small and transient reducing effects on food intake and body weight in DIO mice.
Why this rating
The claim is based on direct experimental results from the study.
Source
Characterization of 0839 – A tool compound for pre-clinical mode-of-action studies of amylin analogues such as cagrilintide
Sanaz Gabery et al. · Life Sciences · 2025
DOI 10.1016/j.lfs.2025.123845
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Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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