Research
Hormonal
Both systolic blood pressure (SBP) and weight reductions are independently associated with reduced MACE risk.
Weight management and blood pressure control should be emphasized in treatment plans for these patients.
StrongSupportsmedium confidence
Meta-regression revealed that both SBP and weight reductions were independently associated with MACE risk reduction.
Why this rating
Based on a meta-analysis of randomized controlled trials.
Source
Ambulatory blood pressure monitoring strengthens the cardiovascular signal of GLP-1RA: a meta-analysis of blood pressure and weight mediation
Nicolás Renna et al. · Journal of Hypertension · 2025
DOI 10.1097/hjh.0000000000004158
Meta-analysis
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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