Research
Metabolic adaptation
Key secondary endpoints include categorical weight-loss thresholds, changes in anthropometric and cardiometabolic measures, and comprehensive safety and tolerability assessments.
The trial will assess various health metrics alongside weight loss to evaluate overall impact.
StrongSupportsmedium confidence
Key secondary endpoints include categorical weight-loss thresholds, changes in anthropometric and cardiometabolic measures, and comprehensive safety and tolerability assessments.
Why this rating
Based on the structured design of the trial.
Source
Efsubaglutide alfa in adults with overweight or obesity: Protocol for a seamless, adaptive phase 2b/3 randomized, double‐blind, placebo‐controlled trial ( <scp>LIGHT</scp> 2)
WEIPING JIA et al. · Diabetes Obesity and Metabolism · 2026
rct
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