Research

Metabolic adaptation

A high-protein diet, alone or combined with resistance training, induces modest but measurable metabolic shifts without disrupting global metabolic homeostasis.

Older adults can safely increase protein intake without adverse metabolic effects, especially when combined with exercise.

StrongSupportsmedium confidence
These findings suggest that older adults can adapt to elevated protein intake while maintaining metabolic stability, supporting the metabolic safety of a high-protein diet in combination with resistance exercise.
Hannah Spahits et al. · Age and Ageing · 2026

Why this rating

Based on the randomized controlled trial design described in the abstract.

Source

Impact of a high-protein diet with and without strength training over 17 weeks on the plasma metabolome in older adults

Hannah Spahits et al. · Age and Ageing · 2026

rct · n=136
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