Research
Energy balance
Cardiovascular events did not decrease in obese and overweight diabetics despite a median weight loss of 6%.
Weight loss alone may not be sufficient to improve cardiovascular health in this population.
StrongRefutesmedium confidence
cardiovascular events (heart disease, stroke, and cardiovascular-related deaths) did not decrease in obese and overweight diabetics despite these participants losing 6% of their body weight.
Why this rating
Based on a large, multicenter trial with a significant follow-up period.
Source
Efficacy of Commercial Weight-Loss Programs
James T. Langland · Annals of Internal Medicine · 2015
DOI 10.7326/l15-5130
Meta-analysis
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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