Research
Metabolic adaptation
Face-to-face interventions demonstrated a significant 46% risk reduction in T2DM incidence and a 46% increase in the reversion to normoglycemia compared with the control group.
Practitioners should prioritize face-to-face interventions for effective T2DM prevention and normoglycemia reversion.
StrongSupportsmedium confidence
Our analysis showed that face-to-face interventions demonstrated a significant 46% risk reduction in T2DM incidence (risk ratio [RR] 0.54, 95% CI 0.47-0.63; I²=43%; P<.001), and a 46% increase in the reversion to normoglycemia (RR 1.46, 95% CI 1.11-1.91; I²=82%; P=.006), when compared with the control group.
Why this rating
Based on the meta-analysis of randomized controlled trials.
Source
Effectiveness of Different Intervention Modes in Lifestyle Intervention for the Prevention of Type 2 Diabetes and the Reversion to Normoglycemia in Adults With Prediabetes: Systematic Review and Meta-Analysis of Randomized Controlled Trials (Preprint)
Yachen Wang et al. · 2024
DOI 10.2196/preprints.63975
Meta-analysis
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Digital health interventions were associated with a 12% risk reduction in T2DM incidence compared with the control group.Strong
- Blended interventions combining digital and face-to-face approaches suggested a 37% risk reduction in T2DM incidence and an 87% increase in the reversion to normoglycemia.Strong
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