Research
Hormonal
24-hour plasma free cortisol levels increase with age in association with increased CPR, independent of body size.
Aging is associated with increased cortisol production, which may influence health and body composition.
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In addition, 24-h plasma free cortisol levels were increased with age in association with increased CPR, independent of body size.
Why this rating
The study design supports the measurement of cortisol levels across different ages.
Source
Association of 24-Hour Cortisol Production Rates, Cortisol-Binding Globulin, and Plasma-Free Cortisol Levels with Body Composition, Leptin Levels, and Aging in Adult Men and Women
Jonathan Q. Purnell et al. · The Journal of Clinical Endocrinology & Metabolism · 2004
DOI 10.1210/jc.2003-030440
cross-sectional · n=54Cited 197×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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