Research
Energy balance
No significant linkages were found between polymorphic microsatellite markers and obesity-related traits in Pima Indians.
This suggests that the studied genetic markers may not be useful for predicting obesity in this population.
StrongRefutesmedium confidence
No significant linkages were found in an analysis of all sibships or in an analysis restricted to discordant sib pairs.
Why this rating
Based on the analysis of a large sample size of 716 Pima Indians.
Source
Absence of Linkage of Obesity and Energy Metabolism to Markers Flanking Homologues of Rodent Obesity Genes in Pima Indians
Rod A Norman et al. · Diabetes · 1996
DOI 10.2337/diab.45.9.1229
other · n=716Cited 55×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
Related findings · Energy balance
- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →