Research
Molecular
Insulin resistance is likely a polygenic disorder influenced by genetic predisposition.
Genetic factors should be considered in the assessment and management of insulin resistance.
StrongSupportsmedium confidence
Indeed, it is very likely to be a polygenic disorder in most individuals.
Why this rating
The claim is based on genetic associations observed in populations.
Source
The insulin resistance syndrome and coronary artery disease
David M. Kendall et al. · Coronary Artery Disease · 2003
DOI 10.1097/01.mca.0000076512.29238.2a
reviewCited 61×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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- Insulin resistance is characterized by an impaired physiological response to insulin and is associated with central obesity, hypertension, dyslipidemia, glucose intolerance, and specific abnormalities of endothelial cell and vascular function.Strong
- There is a strong association between insulin resistance syndrome and the risk of cardiovascular disease.Strong
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