Research
Hormonal
There were no differences in fasting plasma leptin concentrations between insulin-sensitive and insulin-resistant subjects after adjusting for percent body fat.
Insulin resistance does not appear to influence leptin levels when body fat is controlled for.
StrongRefutesmedium confidence
After adjusting for percent body fat, there were no differences in fasting plasma leptin concentrations between insulin-sensitive and insulin-resistant subjects.
Why this rating
The claim is based on direct measurements and statistical analysis.
Source
Effects of acute hyperinsulinemia on plasma leptin concentrations in insulin-sensitive and insulin-resistant Pima Indians.
Richard E. Pratley et al. · The Journal of Clinical Endocrinology & Metabolism · 1996
DOI 10.1210/jcem.81.12.8954052
other · n=26Cited 68×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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