Research
Hormonal
Plasma leptin concentrations did not change in response to insulin in either the insulin-sensitive or insulin-resistant subjects.
Insulin does not appear to influence leptin levels acutely, which may have implications for metabolic regulation.
StrongRefutesmedium confidence
Plasma leptin concentrations did not change in response to insulin in either the insulin-sensitive or insulin-resistant subjects.
Why this rating
The claim is based on controlled experimental conditions and direct measurements.
Source
Effects of acute hyperinsulinemia on plasma leptin concentrations in insulin-sensitive and insulin-resistant Pima Indians.
Richard E. Pratley et al. · The Journal of Clinical Endocrinology & Metabolism · 1996
DOI 10.1210/jcem.81.12.8954052
other · n=26Cited 68×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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