Research
Molecular
Addressing insulin resistance is important in the management of T2DM.
Clinicians should prioritize addressing insulin resistance in T2DM treatment plans.
StrongSupportsmedium confidence
discuss the importance of addressing IR in the management of T2DM.
Why this rating
The claims are based on a review of established mechanisms and clinical implications.
Source
Insulin Resistance the Link between T2DM and CVD: Basic Mechanisms and Clinical Implications
Muhammad Abdul‐Ghani et al. · Current Vascular Pharmacology · 2017
DOI 10.2174/1570161115666171010115119
reviewCited 77×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Insulin resistance (IR) is a cardinal feature of type 2 diabetes mellitus (T2DM) and contributes to elevated cardiovascular disease (CVD) risk.Strong
- Improving insulin sensitivity is anticipated to lower plasma glucose concentration and decrease CVD risk in T2DM patients, independent of glucose control.Strong
Related findings · Molecular
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- Normalization of 10-year cardiovascular risk and heart age is possible after substantial dietary weight loss and remission of T2DM.Strong
- The Low-Fat Plus diet resulted in a greater reduction in total cholesterol compared to the Low-Fat diet, with changes of -0.46 mmol/L (-17.6 mg/dL) versus -0.24 mmol/L (-9.2 mg/dL) respectively (P = 0.01).Strong
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