Mixed
Bariatric surgery significantly reduces the incidence of new-onset type 2 diabetes, hypertension, and dyslipidemia in severely obese individuals compared to no intervention.
For severely obese individuals, bariatric surgery is a highly effective preventive measure against developing type 2 diabetes, high blood pressure, and high cholesterol. The study shows that surgery reduces the risk of developing these conditions by 55-94% compared to no treatment. This should be a key factor in treatment decisions for severe obesity, especially in regions with high metabolic disease rates.
The relative risk reductions associated with bariatric surgery were 94, 93, and 55% for the development of T2DM, HTN, and dyslipidemia, respectively.
Why this rating
Prospective cohort study with large sample size (612 surgery, 593 control) and long follow-up (3+ years), but lacks randomization.
Source
The effect of bariatric surgery in comparison with the control group on the prevention of comorbidities in people with severe obesity: a prospective cohort study
Amir Ebadinejad et al. · BMC Surgery · 2022
DOI 10.1186/s12893-022-01740-7
Related findings · Mixed
- Bariatric surgery (VSG and RYGB) is the most effective and sustainable treatment for obesity, producing marked and sustained weight loss that non-surgical interventions cannot match.Strong
- Severely protein-deficient diets (2–3% energy) induce lean body mass loss and metabolic imbalance, whereas adequate protein intake (0.66 g/kg/d minimum) is a prerequisite for maintaining muscle, bone, and physiological function.Strong
- For patients with Class III obesity (BMI >39.9 kg/m2), metabolic bariatric surgery (MBS) is significantly more effective than any currently approved medication, with BilioPancreatic Diversion (BPD) showing the highest estimated weight loss.Strong
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