Macro partitioning
Reducing saturated fat intake significantly reduces combined cardiovascular events in adults, with moderate certainty of evidence.
To lower your risk of heart attacks and other cardiovascular events, consider reducing your intake of saturated fats (found in red meat, full-fat dairy, and tropical oils) and replacing them with unsaturated fats (found in olive oil, nuts, seeds, and fish). This change is supported by moderate-quality evidence from randomized trials and shows a significant reduction in combined cardiovascular events, even if it doesn't immediately change your risk of death.
The effect of reduction in SAF intake on combined cardiovascular events (RR 0.79, 95%CI 0.66–0.93) was graded as having moderate certainty of evidence.
Why this rating
Moderate certainty based on GRADE assessment of RCTs, though heterogeneity was high (I2=65%).
Source
Effect of reducing saturated fat intake on cardiovascular disease in adults: an umbrella review
Adolfo Aramburú et al. · Frontiers in Public Health · 2024
DOI 10.3389/fpubh.2024.1396576
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