Research
Metabolic adaptation
Metformin and topiramate are commonly prescribed for weight gain in individuals with SMI, but their weight loss potential is modest.
Practitioners should consider the limited effectiveness of metformin and topiramate for weight management in SMI patients.
StrongQualifiesmedium confidence
Metformin and topiramate along with lifestyle interventions are commonly prescribed for weight gain in individuals with SMI; however, their weight loss potential is modest at best.
Why this rating
The claim is based on established clinical practices.
Source
Promising translatable pharmacological interventions for body weight management in individuals with severe mental illness – a narrative review
Riddhita De et al. · Expert Opinion on Pharmacotherapy · 2023
reviewCited 4×
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