Mixed
Daily consumption of a multi-ingredient supplement (whey protein, creatine, vitamin D, n-3 PUFA) for 7 weeks does not significantly alter resting or acute exercise-stimulated myofibrillar protein synthesis (MyoPS) in overweight older men compared to a control beverage.
For older overweight men, simply adding a multi-ingredient supplement (protein, creatine, vitamins) twice daily for several weeks does not necessarily boost muscle protein synthesis rates beyond what the body naturally does with exercise. Focus on consistent resistance training rather than expecting supplements to automatically amplify muscle growth signals.
We observed that 7 weeks of whey protein-based multi-ingredient supplementation did not augment the MyoPS response to an acute bout of RE.
Why this rating
Randomized controlled trial with objective biomarkers (deuterated water), but small sample size (n=15) and null findings limit generalizability.
Source
Integrated Myofibrillar Protein Synthesis in Recovery From Unaccustomed and Accustomed Resistance Exercise With and Without Multi-ingredient Supplementation in Overweight Older Men
Kirsten E. Bell et al. · Frontiers in Nutrition · 2019
DOI 10.3389/fnut.2019.00040
Related findings · Mixed
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