Research
Energy balance
79% of studies testing weight loss as a mechanism found no support or found that interventions were less effective/harmful for fatter people.
Practitioners should be cautious about relying on weight loss as a mechanism for DPP effectiveness.
StrongRefutesmedium confidence
Of those, 79% either found no support or found that interventions were less effective/harmful for fatter people.
Why this rating
Based on the systematic review of 108 studies.
Source
Potential mechanisms for change in diabetes prevention programs: A systematic review
Margit I. Berman et al. · Diabetic Medicine · 2026
DOI 10.1111/dme.70249
systematic_review · n=502257
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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