Research
Molecular
Atherogenicity (ATI) and Thrombogenicity (THI) indices are strongly associated with long-term coronary heart disease (CHD) mortality.
Practitioners should consider the impact of dietary fatty acids on long-term CHD risk.
StrongSupportsmedium confidence
ATI and THI indices assembled by pooling several types of dietary fatty acids are strongly associated with long-term CHD mortality.
Why this rating
Based on the analysis of 16 cohorts over a long follow-up period.
Source
The lipid-heart hypothesis from the Seven Countries Study of Cardiovascular Diseases
Alessandro Menotti et al. · Current Opinion in Lipidology · 2025
DOI 10.1097/mol.0000000000000993
cohort · n=16
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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