Research
Metabolic adaptation
Lower HbA1c is associated with 0.17 to 0.22 standard deviation better cognitive function across all domains.
Improving diabetes control to achieve lower HbA1c levels may enhance cognitive function in individuals with type 2 diabetes.
StrongSupportsmedium confidence
Lower versus high HbA1c was associated with 0.17 to 0.22 standard deviation better cognitive function for all domains (p < 0.001).
Why this rating
Based on a large clinical trial with a significant number of participants.
Source
Associations of modifiable lifestyle and clinical factors with cognitive function in adults with type 2 diabetes
Anahita Golchin et al. · Journal of Diabetes and its Complications · 2025
cohort · n=3723
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