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Younger age (<65 years) and shorter duration of severe neutropenia are the strongest independent predictors of lean mass gain during adapted physical activity in hematology inpatients.

Younger hematology patients (<65) and those with shorter periods of severe neutropenia are likely to see the greatest lean mass benefits from adapted physical activity. Older patients or those with prolonged neutropenia may see minimal gain, but activity remains safe and improves physical function.

ModerateQualifiesMEDIUM confidence
In multivariate analysis, variables that remained significantly associated with relative LM gain were (1) a short duration of neutropenia and (2) a younger age.
Axel Sudria et al. · Blood Neoplasia · 2025

Why this rating

Derived from multivariate analysis of a prospective observational study.

Source

Adapted physical activity for hematology inpatients: focus on lean mass gain

Axel Sudria et al. · Blood Neoplasia · 2025

DOI 10.1016/j.bneo.2025.100183

cohort · n=123
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DOI resolved against Crossref · corpus check 2026-06-10

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