Research
Micronutrients & recovery
Vitamin C and E supplementation (200 IU E and 1000 mg C daily) does not significantly improve functional outcomes, graft rupture rates, or inflammatory markers after ACL reconstruction.
Taking high doses of Vitamin C and E (1000 mg and 200 IU twice daily) does not appear to significantly improve functional outcomes or reduce inflammation after ACL surgery. It is not recommended as a standard part of recovery.
LimitedRefutesLOW confidence
Vitamin C and E are known for their anti‐inflammatory properties, but their benefits during recovery are under debate
Why this rating
Based on RCTs with serious risk of bias.
Source
Nutrition and rehabilitation after anterior cruciate ligament reconstruction: A systematic review
Shaniya Raghoebar et al. · Knee Surgery Sports Traumatology Arthroscopy · 2026
DOI 10.1002/ksa.70441
systematic_review
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- High protein intake combined with physical rehabilitation improves muscle mass retention and functional recovery in patients undergoing ACL reconstruction.Moderate
- Correcting vitamin D insufficiency (levels < 30 ng/mL) may be warranted to prevent greater quadriceps muscle loss and support genomic recovery processes after ACL reconstruction.Moderate
- Supplementation with flaxseed oil (omega-3 fatty acids) and leucine shows some promise for improving recovery outcomes after ACL reconstruction, but high-quality evidence is lacking.Limited
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