Mixed
Metabolic bariatric surgery (MBS) provides superior long-term weight loss and glycemic control compared to non-surgical management in patients with obesity and type 2 diabetes.
For patients with severe obesity and type 2 diabetes, metabolic bariatric surgery offers significantly better long-term weight loss and blood sugar control than non-surgical management. While surgery is not for everyone, those who undergo it maintain much greater weight loss (22% vs 8.6%) and better glycemic control over five years. If surgery is not an option, intensive lifestyle modification and pharmacotherapy are critical alternatives to mitigate health risks.
Patients eligible for MBS who proceed with surgery achieve superior weight loss and glycaemic control compared to those who decide not to proceed with surgery.
Why this rating
Retrospective cohort study with real-world data, large sample size (n=411), and 5-year follow-up, but lacks randomization.
Source
Metabolic bariatric surgery pays off: a longitudinal analysis of weight loss and HbA1c changes in real-world patients data in the West of Scotland
Beatrice J. Leyaro et al. · International Journal of Obesity · 2025
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