Energy balance
Severely Energy-Restricted Diets (SERDs) utilizing meal replacements achieve approximately 10% body mass loss in people with class III obesity (BMI ≥ 40 kg/m2) when followed for 6 weeks or longer.
For individuals with severe obesity (BMI ≥ 40), a medically supervised Severely Energy-Restricted Diet using meal replacements can yield approximately 10% body weight loss if maintained for at least 6 weeks. Success requires strict adherence to the prescribed caloric intake (500-1200 kcal/day depending on the specific protocol), adequate protein supplementation, and engagement with supportive counseling to manage behavioral challenges.
Meal replacement Severely Energy-Restricted Diets (SERDs) produce ~10% loss of body mass when followed for 6 weeks or longer in people with class III obesity (BMI ≥ 40 kg/m2).
Why this rating
Based on clinical trials and validated medical records of a specific cohort, though qualitative in adherence factors.
Source
Dietary adherence and program attrition during a severely energy-restricted diet among people with complex class III obesity: A qualitative exploration
Gabrielle Maston et al. · PLoS ONE · 2021
DOI 10.1371/journal.pone.0253127
Related findings · Energy balance
- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →