Energy balance
Sustained weight loss of 15 kg or more through structured lifestyle interventions (such as total meal replacement diets) can induce remission of type 2 diabetes in early-stage patients.
If you have early-stage type 2 diabetes, losing a significant amount of weight (around 15 kg or 33 lbs) through a structured program can potentially put your diabetes into remission. This often involves a short period of very low-calorie intake (around 800-850 calories/day) using meal replacements, followed by a careful return to normal food. This is most effective when done under professional guidance and is most likely to work if you haven't had diabetes for very long.
In the weight management program group, 36% of patients with T2DM underwent remission compared to 3.4% in the usual care group... The 2-year results of DiRECT support the notion that intensive lifestyle intervention for weight loss can lead to sustained remission in early-stage T2DM.
Why this rating
Supported by multiple randomized controlled trials (DiRECT, STANDby, DIADEM-I) and large observational studies (SOS).
Source
Treat Obesity to Treat Type 2 Diabetes Mellitus
Cem Sulu et al. · Diabetes Therapy · 2024
DOI 10.1007/s13300-024-01536-3
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- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
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