Mixed
Combining a multi-ingredient nutritional supplement (n-3 PUFA, whey protein, creatine, vitamin D, calcium) with 12 weeks of resistance exercise training and high-intensity interval training improves composite cognitive function, verbal memory, and processing speed in healthy older men.
For healthy older men, combining a specific multi-ingredient supplement (containing omega-3s, protein, creatine, vitamin D, and calcium) with a structured exercise program (resistance training twice a week and high-intensity interval training once a week) for 12 weeks can improve overall cognitive function, memory, and processing speed. The supplement alone did not improve cognition, and exercise alone had mixed results on composite scores, suggesting the combination is key. Ensure you are healthy enough for high-intensity exercise and consult a doctor before starting.
Our results show that 12 weeks of RET + HIIT resulted in improved MOCA scores, word recall, and reaction time during an executive functions task; and suggest that a multi-ingredient supplement combined with this exercise training program may improve composite cognitive function scores in older men possibly via supplementation-mediated alterations to n−3 PUFA bioavailability.
Why this rating
Randomized controlled trial with a relatively small sample size (n=49) and short duration (20 weeks), but rigorous blinding and standardized testing.
Source
A Multi-Ingredient Nutritional Supplement in Combination With Resistance Exercise and High-Intensity Interval Training Improves Cognitive Function and Increases N-3 Index in Healthy Older Men: A Randomized Controlled Trial
Kirsten E. Bell et al. · Frontiers in Aging Neuroscience · 2019
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