Research
Micronutrients & recovery
Specific micronutrients (folate, choline, resveratrol, EGCG) can mitigate toxin-induced epigenetic damage by altering DNA methylation and histone modification patterns.
Ensure adequate intake of methyl-donors (folate, choline, B vitamins) and antioxidants (resveratrol, EGCG) to help mitigate the epigenetic damage caused by environmental toxins like smoke and alcohol.
ModerateSupportsMEDIUM confidence
Nutrients from our diet can upregulate or downregulate the expression of enzymes involved in these epigenetic processes... For example, when genes encoding for HDAC are methylated by the addition of the micronutrient resveratrol, this can lead to decreased expression of pro-inflammatory markers such as TNF-alpha.
Why this rating
Supported by multiple animal studies cited in the review.
Source
Timing of dietary effects on the epigenome and their potential protective effects against toxins
Lynnea A. Nicholls et al. · Epigenetics · 2025
narrative_reviewCited 5×
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