Mixed
In overweight/obese individuals with type 2 diabetes free from complications, peak oxygen consumption (VO2peak) is impaired due to reduced skeletal muscle oxygenation and blood volume during exercise, despite normal pulmonary function and arterial oxygen transport.
If you have Type 2 Diabetes without complications, your reduced exercise stamina is likely not due to lung problems but rather how your muscles handle blood flow and oxygen during intense effort. To improve your fitness, focus on exercise programs that enhance skeletal muscle perfusion and blood flow, such as combining aerobic exercise with resistance training, rather than focusing on respiratory mechanics.
Individuals with type 2 diabetes free from complications displayed normal pulmonary function at rest and post exercise. However, impaired skeletal muscle oxygenation during exercise, resulting from reduced limb blood volume and altered muscle deoxygenation, may contribute to the lower VO2peak observed in this population.
Why this rating
Randomized comparative clinical trial with matched controls, though sample size is small (n=30).
Source
Impaired muscle oxygenation despite normal pulmonary function in type 2 diabetes without complications
Islem Jlali et al. · American Journal of Physiology-Endocrinology and Metabolism · 2024
DOI 10.1152/ajpendo.00392.2023
Related findings · Mixed
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