Research
Mixed
Obesity (BMI ≥ 30 kg/m²) is associated with the highest risk of incident atrial fibrillation and ischemic stroke in young adults (20-39 years), with risk attenuating significantly in those over 60.
Maintain a healthy weight starting in your 20s. The cardiovascular damage from obesity (atrial fibrillation and stroke risk) is most potent when you are young. Waiting until middle age to manage weight misses the window where obesity causes the most severe relative risk increase.
StrongQualifiesHIGH confidence
The highest hazard ratio (HR) of the BMI ≥ 30 kg/m2 group was observed in subjects aged 30–39 years [HR 1.80, 95% CI 1.63–1.98, p < 0.001]... Among the BMI ≥ 30 kg/m2 groups, subjects aged 20–29 years presented the highest risk of IS [HR 3.00, 95% CI (2.34–3.84), p < 0.001].
Why this rating
Large-scale population-based cohort (n=9.4 million) with long follow-up.
Source
Associations between obesity parameters and the risk of incident atrial fibrillation and ischaemic stroke in the different age groups
Hyo‐Jeong Ahn et al. · Frontiers in Cardiovascular Medicine · 2022
cohort · n=9432332Cited 12×
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