Research

Mixed

Higher intake of ultra-processed foods is associated with a significantly increased risk of developing inflammatory bowel disease (IBD), including both Crohn's disease and ulcerative colitis.

To lower your risk of inflammatory bowel disease, focus on reducing ultra-processed foods. This includes soft drinks, refined sweetened foods (candy, pastries), salty snacks, and processed meats. You do not need to avoid natural foods like meat, dairy, or vegetables, as the study found no link between those and IBD risk. The key is minimizing items with additives and preservatives, which may disrupt gut health.

GoodSupportsHIGH confidence
Higher intake of ultra-processed food was associated with a higher risk of incident IBD (hazard ratio 1.82, 95% confidence interval 1.22 to 2.72 for ≥5 servings/day and 1.67, 1.18 to 2.37 for 1-4 servings/day compared with <1 serving/day, P=0.006 for trend).
Neeraj Narula et al. · BMJ · 2021

Why this rating

Large prospective cohort (n=116,087), multi-country, long follow-up (median 9.7 years), adjusted for confounders, but relies on self-reported FFQ and self-reported diagnosis.

Source

Association of ultra-processed food intake with risk of inflammatory bowel disease: prospective cohort study

Neeraj Narula et al. · BMJ · 2021

DOI 10.1136/bmj.n1554

cohort · n=116087Cited 353×
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

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