Research

Hormonal

High consumption of long-chain omega-3 fatty acids is associated with a significantly lower risk of developing laparoscopically confirmed endometriosis.

Focus on increasing intake of long-chain omega-3 fatty acids, primarily found in fatty fish (like tuna and dark fish) and certain salad dressings, as higher consumption is linked to a lower risk of endometriosis in large prospective studies. This does not mean avoiding all fats, as total fat intake showed no association, but rather prioritizing specific beneficial fatty acids.

GoodSupportsHIGH confidence
those women in the highest fifth of long-chain omega-3 fatty acid consumption were 22% less likely to be diagnosed with endometriosis compared with those with the lowest fifth of intake [95% confidence interval (CI) = 0.62–0.99; P-value, test for linear trend (Pt) = 0.03].
Stacey A. Missmer et al. · Human Reproduction · 2010

Why this rating

Large prospective cohort (Nurses' Health Study II), long follow-up (12 years), and laparoscopic confirmation of cases provide high observational validity, though causality cannot be strictly proven.

Source

A prospective study of dietary fat consumption and endometriosis risk

Stacey A. Missmer et al. · Human Reproduction · 2010

DOI 10.1093/humrep/deq044

cohort · n=70709Cited 238×
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DOI resolved against Crossref · corpus check 2026-06-10

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