Hormonal
High cardiorespiratory fitness combined with low saturated fat intake attenuates the negative impact of high waist circumference on early-phase insulin secretion (DI30) in women.
If you have a higher waist circumference, focus on building cardiorespiratory fitness and reducing saturated fat intake. This combination can significantly protect your body's ability to secrete insulin in response to glucose, especially if you are a woman. It is not just about weight loss; fitness and diet quality matter independently.
The negative association of high WC with DI30 was attenuated by a combination of low SF intake and high cardiorespiratory fitness.
Why this rating
Population-based observational study with objective measures (VO2max, OGTT) and large sample size (n=1114), but cross-sectional baseline data limits causal inference.
Source
Diet, insulin secretion and insulin sensitivity – the Dose–Responses to Exercise Training (DR's EXTRA) Study (ISRCTN45977199)
Harri M. Heikkilä et al. · British Journal Of Nutrition · 2014
DOI 10.1017/s0007114514002426
More from this paper
- Higher dietary fiber intake is positively associated with whole-body insulin sensitivity (Matsuda-IS) independent of cardiorespiratory fitness and waist circumference.Good
- In women with high waist circumference, low saturated fat intake combined with high fitness significantly preserves early-phase insulin secretion (DI30) compared to those with suboptimal lifestyle profiles.Good
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