Mixed
A 4-week low-carbohydrate diet (25% carbs, 45% protein, 30% fat) significantly reduces body weight, BMI, and body fat in obese adults while shifting gut microbiota composition by decreasing Firmicutes and increasing Bacteroidetes.
Adopt a low-carbohydrate diet for 4 weeks, aiming for 25% carbs, 45% protein, and 30% fat. Calculate your daily calories based on your ideal body weight (ideal weight in kg multiplied by 20-25, then by 0.75). Focus on high-protein foods, non-starchy vegetables, and use meal replacements if needed to stay on track. Drink at least 1.8 liters of water daily. This approach has been shown to significantly reduce body weight, BMI, and body fat, while improving gut microbiota diversity.
After intervention with the LCD for 4 weeks, a significant reduction in the body weight (−6.14 kg [95% CI, −5.37 to −6.92 kg]; p < 0.001) and BMI (−2.26 kg/m2 [95% CI, −1.96 to −2.56 kg/m2]; p < 0.01) of the participants was noted... Specifically, the relative abundance of Firmicutes was significantly reduced from 73.61% at baseline to 60.26% at week 4. In contrast, the relative abundance of Bacteroidota was significantly increased from 16.13% at baseline to 30.73% at week 4.
Why this rating
Single-arm before-after study with a small sample size (n=43) and short duration (4 weeks), lacking a control group.
Source
Gut microbiota changes associated with low-carbohydrate diet intervention for obesity
Li Li et al. · Open Life Sciences · 2024
DOI 10.1515/biol-2022-0803
Related findings · Mixed
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