Mixed
Virtual weight care programs prescribing a broad range of antiobesity medications alongside behavior change achieve clinically significant weight loss (mean 8.0% at 12 months) in real-world settings, with higher engagement correlating with greater weight loss.
Engage with a structured virtual weight care program that combines medication with behavioral support. Higher engagement with the program (logging weight weekly, interacting with coaches) correlates with greater weight loss (up to 12%). You do not need the most expensive medications to achieve significant results; a broad range of medications, when paired with consistent engagement, can lead to clinically meaningful weight loss.
At 12 months, the mean percent weight loss was 8.0%... Weight loss outcomes increased with program engagement. At 12 months, those engaging at least once weekly lost 10.0% of body weight, while those logging weight at least weekly lost 12.0%.
Why this rating
Large retrospective cohort (n=66,094) with 12-month data, but lacks a control group and relies on self-reported data.
Source
Long‐Term Weight Loss Outcomes in a Virtual Weight Care Clinic Prescribing a Broad Range of Medications Alongside Behavior Change
Jennifer M. Clark et al. · Obesity Science & Practice · 2025
DOI 10.1002/osp4.70036
Related findings · Mixed
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