Research
Hormonal
A high omega-6 to omega-3 fatty acid ratio in the diet contributes to increased incidence of cardiovascular disease and inflammatory disorders by promoting the production of proinflammatory eicosanoids and cytokines.
To reduce inflammation and cardiovascular risk, aim to balance your intake of omega-6 and omega-3 fatty acids. This involves reducing excessive omega-6 intake (common in Western diets) and increasing omega-3 intake, potentially through diet or supplementation.
GoodSupportsHIGH confidence
The increased omega-6/omega-3 ratio in Western diets most likely contributes to an increased incidence of cardiovascular disease and inflammatory disorders.
Why this rating
Supported by epidemiological observations and mechanistic studies.
Source
Omega-3 Fatty Acids in Inflammation and Autoimmune Diseases
Artemis P. Simopoulos · Journal of the American College of Nutrition · 2002
DOI 10.1080/07315724.2002.10719248
narrative_reviewCited 1,990×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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