Research

Macro partitioning

Replacing 2% of energy intake from trans unsaturated fat with unhydrogenated unsaturated fats reduces the risk of coronary heart disease in women by 53%.

Eliminate trans fats from your diet to significantly lower your heart disease risk. Specifically, replace just 2% of your daily calories from trans fats (found in some fried foods and baked goods made with partially hydrogenated oils) with unsaturated fats (like those in olive oil, nuts, or fish). This specific swap is linked to a 53% reduction in heart disease risk.

StrongSupportsHIGH confidence
We estimated that the replacement of 2 percent of energy from trans fat with energy from unhydrogenated, unsaturated fats would reduce risk by 53 percent (95 percent confidence interval, 34 to 67; P<0.001).
Frank B. Hu et al. · New England Journal of Medicine · 1997

Why this rating

Large prospective cohort, long follow-up, rigorous adjustment for confounders.

Source

Dietary Fat Intake and the Risk of Coronary Heart Disease in Women

Frank B. Hu et al. · New England Journal of Medicine · 1997

cohort · n=80082Cited 1,777×
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