Macro partitioning
Replacing 2% of energy intake from trans unsaturated fat with unhydrogenated unsaturated fats reduces the risk of coronary heart disease in women by 53%.
Eliminate trans fats from your diet to significantly lower your heart disease risk. Specifically, replace just 2% of your daily calories from trans fats (found in some fried foods and baked goods made with partially hydrogenated oils) with unsaturated fats (like those in olive oil, nuts, or fish). This specific swap is linked to a 53% reduction in heart disease risk.
We estimated that the replacement of 2 percent of energy from trans fat with energy from unhydrogenated, unsaturated fats would reduce risk by 53 percent (95 percent confidence interval, 34 to 67; P<0.001).
Why this rating
Large prospective cohort, long follow-up, rigorous adjustment for confounders.
Source
Dietary Fat Intake and the Risk of Coronary Heart Disease in Women
Frank B. Hu et al. · New England Journal of Medicine · 1997
DOI 10.1056/nejm199711203372102
More from this paper
- Replacing 5% of energy intake from saturated fat with unsaturated fats reduces the risk of coronary heart disease in women by 42%, whereas replacing it with carbohydrates yields a smaller benefit.Strong
- Total fat intake is not significantly related to the risk of coronary heart disease in women; the type of fat is the critical determinant.Strong
Related findings · Macro partitioning
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- Trans fats should be completely eliminated from the diet, as they increase LDL cholesterol, decrease HDL cholesterol, and are directly associated with increased coronary risk.Strong
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