Research

Macro partitioning

Total fat intake is not significantly related to the risk of coronary heart disease in women; the type of fat is the critical determinant.

Do not focus on reducing the total amount of fat you eat. Instead, focus on the type of fat. Replacing saturated and trans fats with unsaturated fats (like those in olive oil, nuts, and fish) is the key to heart health, not simply eating less fat.

StrongRefutesHIGH confidence
Total fat intake was not significantly related to the risk of coronary disease (for a 5 percent increase in energy from fat, the relative risk was 1.02; 95 percent confidence interval, 0.97 to 1.07; P=0.55).
Frank B. Hu et al. · New England Journal of Medicine · 1997

Why this rating

Large prospective cohort, long follow-up, rigorous adjustment for confounders.

Source

Dietary Fat Intake and the Risk of Coronary Heart Disease in Women

Frank B. Hu et al. · New England Journal of Medicine · 1997

cohort · n=80082Cited 1,777×
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