Research

Energy balance

A lower resting energy expenditure (REE) is a significant risk factor for future body-weight gain in individuals who are not obese.

If you struggle with weight gain despite eating what seems like a normal amount, your resting metabolic rate might be lower than average. This isn't a failure of willpower; it's a biological risk factor. To manage this, you likely need to be more consistent with physical activity and mindful of portion sizes than someone with a higher metabolic rate, as your body burns fewer calories at rest.

GoodSupportsHIGH confidence
We conclude that a low REE is a risk factor for body-weight gain in nonobese subjects.
Éric Ravussin et al. · New England Journal of Medicine · 1988

Why this rating

Longitudinal observational study with 10-year follow-up in a well-defined cohort (Pima Indians), controlling for baseline weight and other factors.

Source

Reduced Rate of Energy Expenditure as a Risk Factor for Body-Weight Gain

Éric Ravussin et al. · New England Journal of Medicine · 1988

DOI 10.1056/nejm198802253180802

cohort · n=10Cited 1,221×
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DOI resolved against Crossref · corpus check 2026-06-10

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